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Establishment of medial fates along the proximo-distal axis of the Drosophila leg through direct activation of dachshund by Distalless

The proximo-distal (PD) axis of the Drosophila leg is thought to be established by the combined gradients of two secreted morphogens, Wingless (Wg) and Decapentaplegic (Dpp). According to this model, high [Wg+Dpp] activates Distalless (Dll) and represses dachshund (dac) in the distal cells of the le...

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Detalhes bibliográficos
Main Authors: Giorgianni, Matt W., Mann, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087180/
https://ncbi.nlm.nih.gov/pubmed/21497759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.03.017
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