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Immunoregulatory Pathways Controlling Progression of Autoimmunity in NOD Mice: The Role of CTLA-4 and TGF-β
The activation, expansion, and survival of regulatory T cells (Tregs) as well as the expression of their suppressive capacities result from distinct signaling pathways involving various membrane receptors and cytokines. Multiple studies have shown that thymus-derived naturally occurring Tregs consti...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3087168/ https://ncbi.nlm.nih.gov/pubmed/19120317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1447.046 |
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