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Tyrosine Phosphatase TpbA of Pseudomonas aeruginosa Controls Extracellular DNA via Cyclic Diguanylic Acid Concentrations

Inactivating the tyrosine phosphatase TpbA of Pseudomonas aeruginosa PA14 induces biofilm formation by 150-fold via increased production of the second messenger cyclic diguanylic acid (c-di-GMP). Here, we show the tpbA mutation reduces extracellular DNA (eDNA) and that increased expression of tpbA i...

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Detalhes bibliográficos
Main Authors: Ueda, Akihiro, Wood, Thomas K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087157/
https://ncbi.nlm.nih.gov/pubmed/21552365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1758-2229.2010.00171.x
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