Activin A, p15(INK4b) Signaling, and Cell Competition Promote Stem/Progenitor Cell Repopulation of Livers in Aging Rats

BACKGROUND & AIMS: Highly proliferative fetal liver stem/progenitor cells (FLSPC) repopulate livers of normal recipients by cell competition. We investigated the mechanisms by which FLSPC repopulate livers of older, compared with younger rats. METHODS: Fetal liver cells were transplanted from DP...

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Main Authors: Menthena, Anuradha, Koehler, Christoph I., Sandhu, Jaswinderpal S., Yovchev, Mladen I., Hurston, Ethel, Shafritz, David A., Oertel, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087123/
https://ncbi.nlm.nih.gov/pubmed/21147108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.12.003
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