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Carbon Isotopes Profiles of Human Whole Blood, Plasma, Red Blood Cells, Urine and Feces for Biological/Biomedical (14)C-Accelerator Mass Spectrometry Applications
Radiocarbon ((14)C) is an ideal tracer for in vivo human ADME (absorption, distribution, metabolism, elimination) and PBPK (physiological-based pharmacokinetic) studies. Living plants preferentially incorporate atmospheric (14)CO(2), vs (13)CO(2), vs (12)CO(2), which result in unique signature. Furt...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086998/ https://ncbi.nlm.nih.gov/pubmed/21452856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac103038s |
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