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Increased Clearance of Morphine in Sickle Cell Disease: Implications for Pain Management
Acute vaso-occlusive painful episodes associated with sickle cell disease (SCD) are frequently treated with morphine. Many SCD individuals require relatively higher doses of morphine to achieve optimal analgesia. We studied pharmacokinetics of morphine in SCD to explore if altered disposition could...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086992/ https://ncbi.nlm.nih.gov/pubmed/21277838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2010.10.012 |
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