XPC silencing in normal human keratinocytes triggers metabolic alterations through NOX-1 activation-mediated reactive oxygen species

Cancer cells utilize complex mechanisms to remodel their bioenergetic properties. We exploited the intrinsic genomic stability of xeroderma pigmentosum C (XPC) to understand the interrelationships between genomic instability, reactive oxygen species (ROS) generation, and metabolic alterations during...

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Detalhes bibliográficos
Main Authors: Rezvani, Hamid Reza, Rossignol, Rodrigue, Ali, Nsrein, Benard, Giovanni, Tang, Xiuwei, Yang, Hee Seung, Jouary, Thomas, de Verneuil, Hubert, Taïeb, Alain, Kim, Arianna L., Mazurier, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086958/
https://ncbi.nlm.nih.gov/pubmed/21167810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2010.12.006
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