Novel CCL21-Vault Nanocapsule Intratumoral Delivery Inhibits Lung Cancer Growth

BACKGROUND: Based on our preclinical findings, we are assessing the efficacy of intratumoral injection of dendritic cells (DC) transduced with an adenoviral vector expressing the secondary lymphoid chemokine (CCL21) gene (Ad-CCL21-DC) in a phase I trial in advanced non-small cell lung cancer (NSCLC)...

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Detalhes bibliográficos
Main Authors: Kar, Upendra K., Srivastava, Minu K., Andersson, Åsa, Baratelli, Felicita, Huang, Min, Kickhoefer, Valerie A., Dubinett, Steven M., Rome, Leonard H., Sharma, Sherven
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086906/
https://ncbi.nlm.nih.gov/pubmed/21559281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018758
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