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An Adhesion-Dependent Switch between Mechanisms That Determine Motile Cell Shape

Keratocytes are fast-moving cells in which adhesion dynamics are tightly coupled to the actin polymerization motor that drives migration, resulting in highly coordinated cell movement. We have found that modifying the adhesive properties of the underlying substrate has a dramatic effect on keratocyt...

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Detalhes bibliográficos
Main Authors: Barnhart, Erin L., Lee, Kun-Chun, Keren, Kinneret, Mogilner, Alex, Theriot, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086868/
https://ncbi.nlm.nih.gov/pubmed/21559321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001059
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