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Functionalized Scaffold-mediated Interleukin 10 Gene Delivery Significantly Improves Survival Rates of Stem Cells In Vivo

While stem cell transplantation could potentially treat a variety of disorders, clinical studies have not yet demonstrated conclusive benefits. This may be partly because transplanted stem cells have low survival rates, potentially due to host inflammation. The system described herein used two diffe...

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Bibliografiske detaljer
Main Authors: Holladay, Carolyn, Power, Karen, Sefton, Michael, O'Brien, Timothy, Gallagher, William M., Pandit, Abhay
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086863/
https://ncbi.nlm.nih.gov/pubmed/21266957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.311
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