TRPV1-antagonist AMG9810 promotes mouse skin tumorigenesis through EGFR/Akt signaling

In addition to capsaicin, a transient receptor potential channel vanilloid subfamily 1 (TRPV1) agonist, two kinds of antagonists against this receptor are used as therapeutic drugs for pain relief. Indeed, a number of small molecule TRPV1 antagonists are currently undergoing Phase I/II clinical tria...

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Bibliografiske detaljer
Main Authors: Li, Shengqing, Bode, Ann M., Zhu, Feng, Liu, Kangdong, Zhang, Jishuai, Kim, Myoung Ok, Reddy, Kanamata, Zykova, Tatyana, Ma, Wei-ya, Carper, Andria L., Langfald, Alyssa K., Dong, Zigang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Carcinogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086704/
https://ncbi.nlm.nih.gov/pubmed/21349818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr037
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