MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer

MiR-145 is downregulated in various cancers including prostate cancer. However, the underlying mechanisms of miR-145 downregulation are not fully understood. Here, we reported that miR-145 was silenced through DNA hypermethylation and p53 mutation status in laser capture microdissected (LCM) prostat...

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Detalhes bibliográficos
Main Authors: Suh, Seong O., Chen, Yi, Zaman, Mohd Saif, Hirata, Hiroshi, Yamamura, Soichiro, Shahryari, Varahram, Liu, Jan, Tabatabai, Z.Laura, Kakar, Sanjay, Deng, Guoren, Tanaka, Yuichiro, Dahiya, Rajvir
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086703/
https://ncbi.nlm.nih.gov/pubmed/21349819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr036
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