A Modular System for the Synthesis of Multiplexed Magnetic Resonance Probes

We have developed a modular architecture for preparing high-relaxivity multiplexed probes utilizing click chemistry. Our system incorporates azide bearing Gd(III) chelates and a trialkyne scaffold with a functional group for subsequent modification. In optimizing the relaxivity of this new complex w...

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Main Authors: Mastarone, Daniel J., Harrison, Victoria S.R., Eckermann, Amanda L., Parigi, Giacomo, Luchinat, Claudio, Meade, Thomas J.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086647/
https://ncbi.nlm.nih.gov/pubmed/21413801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1099616
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