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Downstream Targets of GATA3 in the Vestibular Sensory Organs of the Inner Ear

Haploinsufficiency for the transcription factor GATA3 leads to hearing loss in humans. It is expressed throughout the auditory sensory epithelium (SE). In the vestibular organs, GATA3 is limited to the striola reversal zone of the utricle. Stereocilia orientation shifts 180° at this region which con...

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Autors principals: Alvarado, David M, Veile, Rose, Speck, Judith, Warchol, Mark, Lovett, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086404/
https://ncbi.nlm.nih.gov/pubmed/19924793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22149
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