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Apolipoprotein E-Deficient Lipoproteins Induce Foam Cell Formation by Activation of PERK-EIF-2α Signaling Cascade

Transformation of macrophages into foam cells by apolipoprotein (Apo) E-deficient, ApoB48-containing (E(−)/B48) lipoproteins has been shown to be associated with increased phosphorylation of eukaryotic initiation factor-2α (eIF-2α). The present report examined the causal relationship between eIF-2α...

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Detalhes bibliográficos
Main Authors: Zhao, YanFeng, Guo, ZhongMao, Lin, XingHua, Zhou, LiChun, Okoro, Emmanuel U., Fan, GuoHuang, Ramaswamy, Raju, Yang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086298/
https://ncbi.nlm.nih.gov/pubmed/21552349
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