CD4+ T cells inhibit the neu-specific CD8+ T-cell exhaustion during the priming phase of immune responses against breast cancer

Studies conducted in animal model of infectious diseases or H-Y antigen model suggest a crucial role for CD4+ T cells in providing help for CD8+ T-cell memory responses. This concept suggests that inclusion of T helper epitopes in vaccine formulation will result in improved CD8+ T-cell responses. Al...

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Huvudupphovsmän: Kmieciak, Maciej, Worschech, Andrea, Nikizad, Hooman, Gowda, Madhu, Habibi, Mehran, Depcrynski, Amy, Wang, Ena, Godder, Kamar, Holt, Shawn E., Marincola, Francesco M., Manjili, Masoud H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086038/
https://ncbi.nlm.nih.gov/pubmed/20480224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-0942-8
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