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Rabe Rest in Peace: Confirmation of the Rabe-Kindler Conversion of d-Quinotoxine to Quinine. Experimental Affirmation of the Woodward-Doering Formal Total Synthesis of Quinine

The three-step conversion of d-quinotoxine into quinine, as originally reported by Rabe and Kindler in 1918, has been experimentally verified. This conversion serves to re-affirm the formal total synthesis of quinine reported by Woodward and Doering in 1944. [Image: see text]

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Detalhes bibliográficos
Main Authors: Smith, Aaron C., Williams, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085927/
https://ncbi.nlm.nih.gov/pubmed/18236503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200705421
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