Chronic Fine Particulate Matter Exposure Induces Systemic Vascular Dysfunction via NADPH Oxidase and TLR4 Pathways

RATIONALE: Chronic exposure to ambient air-borne particulate matter <2.5 µm (PM(2.5)) increases cardiovascular risk. The mechanisms by which inhaled ambient particles are sensed and how these effects are systemically transduced remain elusive. OBJECTIVE: To investigate the molecular mechanisms by...

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Autors principals: Kampfrath, Thomas, Maiseyeu, Andrei, Ying, Zhekang, Shah, Zubair, Deiuliis, Jeffrey A., Xu, Xiaohua, Kherada, Nisharahmed, Brook, Robert D., Reddy, Kongara M., Padture, Nitin P., Parthasarathy, Sampath, Chen, Lung Chi, Moffatt-Bruce, Susan, Sun, Qinghua, Morawietz, Henning, Rajagopalan, Sanjay
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085907/
https://ncbi.nlm.nih.gov/pubmed/21273555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.237560
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