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Characterization and Validation of a Streptozotocin-Induced Diabetes Model in the Vervet Monkey
Streptozotocin (STZ), preferentially toxic to pancreatic beta cells, is commonly used to model type 1 diabetes mellitus (DM) in numerous species, including nonhuman primates. We induced DM in twenty vervet monkeys (Chlorocebus aethiops) by intravenous administration of either 45 (n=8, STZ-45) or 55...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085883/ https://ncbi.nlm.nih.gov/pubmed/21356321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vascn.2011.02.003 |
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