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5-Hydroxytryptamine Type 3 Receptor Modulates Opioid-induced Hyperalgesia and Tolerance in Mice

BACKGROUND: Opioid-induced hyperalgesia (OIH) and tolerance are challenging maladaptations associated with opioids in managing pain. Recent genetic studies and the existing literature suggest the 5-hydroxy tryptamine type 3 (5-HT3) receptor participates in these phenomena. The location of the releva...

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Hlavní autoři: Liang, De-Yong, Li, XiangQi, Clark, J. David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085696/
https://ncbi.nlm.nih.gov/pubmed/21368652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31820efb19
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