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Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear

Murine models are ideal for studying cochlear gene transfer as many hearing loss-related mutations have been discovered and mapped within the mouse genome. However, due to its small size and delicate nature, the membranous labyrinth of the mouse is a challenging target for delivery of viral vectors....

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Bibliografiske detaljer
Main Authors: Kilpatrick, Lauren A., Li, Qian, Yang, John, Goddard, John C, Fekete, Donna M., Lang, Hainan
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085601/
https://ncbi.nlm.nih.gov/pubmed/21209625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.175
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