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Low and high affinity dopamine transporter inhibitors block dopamine uptake within 5 sec of intravenous injection
Extensive evidence suggests that the reinforcing effects of cocaine involve inhibition of dopamine transporters (DAT) and subsequent increases in dopamine (DA) levels in the striatum. We have previously reported that cocaine inhibits the DAT within 4–5 sec of intravenous injection, matching the temp...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085557/ https://ncbi.nlm.nih.gov/pubmed/21402130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.03.017 |
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