Tocotrienol-Rich Fraction Prevents Cell Cycle Arrest and Elongates Telomere Length in Senescent Human Diploid Fibroblasts

This study determined the molecular mechanisms of tocotrienol-rich fraction (TRF) in preventing cellular senescence of human diploid fibroblasts (HDFs). Primary culture of HDFs at various passages were incubated with 0.5 mg/mL TRF for 24 h. Telomere shortening with decreased telomerase activity was...

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Hlavní autoři: Makpol, Suzana, Durani, Lina Wati, Chua, Kien Hui, Mohd Yusof, Yasmin Anum, Wan Ngah, Wan Zurinah
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085479/
https://ncbi.nlm.nih.gov/pubmed/21541185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/506171
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