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Imperfect Space Clamp Permits Electrotonic Interactions between Inhibitory and Excitatory Synaptic Conductances, Distorting Voltage Clamp Recordings

The voltage clamp technique is frequently used to examine the strength and composition of synaptic input to neurons. Even accounting for imperfect voltage control of the entire cell membrane (“space clamp”), it is often assumed that currents measured at the soma are a proportional indicator of the p...

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Библиографические подробности
Главные авторы: Poleg-Polsky, Alon, Diamond, Jeffrey S.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085473/
https://ncbi.nlm.nih.gov/pubmed/21559357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019463
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