Catechol-O-Methyltransferase Valine(158)Methionine Polymorphism Modulates Brain Networks Underlying Working Memory Across Adulthood

BACKGROUND: Cognitive abilities decline with age with large individual variability. Genetic variations have been suggested to be an important source for some of this heterogeneity. Among these variations, those related to the dopaminergic system, particularly the valine(158)methionine polymorphism i...

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Detalhes bibliográficos
Main Authors: Sambataro, Fabio, Reed, Jeff D., Murty, Vishnu P., Das, Saumitra, Tan, Hao Yang, Callicott, Joseph H., Weinberger, Daniel R., Mattay, Venkata S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085346/
https://ncbi.nlm.nih.gov/pubmed/19539269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.04.014
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