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Structure of Epstein-Barr Virus glycoprotein 42 suggests a mechanism for triggering receptor-activated virus entry

Epstein-Barr virus requires glycoproteins gH/gL, gB, and gp42 to fuse its lipid envelope with B cells. Gp42 is a type II membrane protein consisting of a flexible N-terminal region, which binds gH/gL, and a C-terminal lectin-like domain that binds to the B cell entry receptor human leukocyte antigen...

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Detalhes bibliográficos
Main Authors: Kirschner, Austin N., Sorem, Jessica, Longnecker, Richard, Jardetzky, Theodore S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085316/
https://ncbi.nlm.nih.gov/pubmed/19217393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.12.010
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