ModEnzA: Accurate Identification of Metabolic Enzymes Using Function Specific Profile HMMs with Optimised Discrimination Threshold and Modified Emission Probabilities

Various enzyme identification protocols involving homology transfer by sequence-sequence or profile-sequence comparisons have been devised which utilise Swiss-Prot sequences associated with EC numbers as the training set. A profile HMM constructed for a particular EC number might select sequences wh...

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Bibliographic Details
Main Authors: Desai, Dhwani K., Nandi, Soumyadeep, Srivastava, Prashant K., Lynn, Andrew M.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085309/
https://ncbi.nlm.nih.gov/pubmed/21541071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/743782
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