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A Novel Algorithm for the Assessment of Blood-Brain Barrier Permeability Suggests That Brain Topical Application of Endothelin-1 Does Not Cause Early Opening of the Barrier in Rats

There are a number of different experimental methods for ex vivo assessment of blood-brain barrier (BBB) opening based on Evans blue dye extravasation. However, these methods require many different steps to prepare the brain and need special equipment for quantification. We here report a novel, simp...

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Библиографические подробности
Главные авторы: Jorks, D., Milakara, D., Alam, M., Kang, E. J., Major, S., Friedman, A., Dreier, J. P.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085294/
https://ncbi.nlm.nih.gov/pubmed/21541244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/169580
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