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Synthetic studies on neoclerodane diterpenes from Salvia splendens: oxidative modifications of ring A

Salvinorin A (1), a neoclerodane diterpene from the hallucinogenic mint Salvia divinorum, is the only known naturally occurring non-nitrogenous and specific κ-opioid agonist. Some oxidative modifications of the A ring in the congeners of 1 isolated from Salvia splendens salviarin, splenolide B, sple...

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Bibliographic Details
Main Authors: Fontana, Gianfranco, Savona, Giuseppe, Rodríguez, Benjamín, Dersch, Christina M., Rothman, Richard B., Prisinzano, Thomas E.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085280/
https://ncbi.nlm.nih.gov/pubmed/21544261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.12.009
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