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The presence of both negative and positive elements in the 5'-flanking sequence of the rat Na,K-ATPase alpha 3 subunit gene are required for brain expression in transgenic mice.

The Na,K-ATPase is an integral plasma membrane protein consisting of alpha and beta subunits, each of which has discrete isoforms expressed in a tissue-specific manner. Of the three functional alpha isoform genes, the one encoding the alpha 3 isoform is the most tissue-restricted in its expression,...

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Détails bibliographiques
Auteurs principaux: Pathak, B G, Neumann, J C, Croyle, M L, Lingrel, J B
Format: Artigo
Langue:Inglês
Publié: 1994
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC308527/
https://ncbi.nlm.nih.gov/pubmed/7984427
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