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Effects of Physiological Variations in Circulating Insulin Levels on Bone Turnover in Humans

CONTEXT: Recent studies in mice have demonstrated that insulin signaling in osteoblasts stimulates bone formation and reduces osteoprotegerin production; the latter results in an increase in bone resorption, which then leads to the release of undercarboxylated osteocalcin from bone. Undercarboxylate...

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Detalhes bibliográficos
Main Authors: Basu, Rita, Peterson, James, Rizza, Robert, Khosla, Sundeep
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085206/
https://ncbi.nlm.nih.gov/pubmed/21325461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-2877
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