Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin

Urtica dioica agglutinin (UDA) is a small plant monomeric lectin, 8.7 kDa in size, with an N-acetylglucosamine specificity that inhibits viruses from Nidovirales in vitro. In the current study, we first examined the efficacy of UDA on the replication of different SARS-CoV strains in Vero 76 cells. U...

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Main Authors: Kumaki, Yohichi, Wandersee, Miles K., Smith, Aaron J., Zhou, Yanchen, Simmons, Graham, Nelson, Nathan M., Bailey, Kevin W., Vest, Zachary G., Li, Joseph K.-K., Chan, Paul Kay-Sheung, Smee, Donald F., Barnard, Dale L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. Published by Elsevier B.V. 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085190/
https://ncbi.nlm.nih.gov/pubmed/21338626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2011.02.003
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