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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

The sensitivity of the commonly used progressive multiple sequence alignment method has been greatly improved for the alignment of divergent protein sequences. Firstly, individual weights are assigned to each sequence in a partial alignment in order to down-weight near-duplicate sequences and up-wei...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Thompson, J D, Higgins, D G, Gibson, T J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1994
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7984417/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.22.4673
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