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Antagonism of orexin 1 receptors eliminates motor hyperactivity and improves homing response acquisition in juvenile rats exposed to alcohol during early postnatal period

Consequences of prenatal alcohol exposure (AE) include motor hyperactivity, disrupted sleep and cognitive deficits. Hypothalamic orexin (ORX)-synthesizing neurons are important for the maintenance of vigilance and regulation of motor activity but their hyperactivity may contribute to anxiety disorde...

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Autors principals: Stettner, Georg M., Kubin, Leszek, Volgin, Denys V.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085169/
https://ncbi.nlm.nih.gov/pubmed/21420437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2011.03.028
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