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Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes
Accurate chromosome segregation requires assembly of the multi-protein kinetochore complex at centromeres. Although prior work identified the centromeric histone H3-variant CENP-A as the important upstream factor necessary for centromere specification, in human cells CENP-A is not sufficient for kin...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085131/ https://ncbi.nlm.nih.gov/pubmed/21529714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.03.031 |
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