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Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes

Accurate chromosome segregation requires assembly of the multi-protein kinetochore complex at centromeres. Although prior work identified the centromeric histone H3-variant CENP-A as the important upstream factor necessary for centromere specification, in human cells CENP-A is not sufficient for kin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gascoigne, Karen E., Takeuchi, Kozo, Suzuki, Aussie, Hori, Tetsuya, Fukagawa, Tatsuo, Cheeseman, Iain M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085131/
https://ncbi.nlm.nih.gov/pubmed/21529714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.03.031
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