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Calculating Sample Size in Trials Using Historical Controls

BACKGROUND: Makuch and Simon [1] developed a sample size formula for historical control trials. When assessing power, they assumed the true control treatment effect to be equal to the observed effect from the historical control group. Many researchers have pointed out that the M-S approach does not...

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Main Authors: Zhang, Song, Cao, Jing, Ahn, Chul
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085081/
https://ncbi.nlm.nih.gov/pubmed/20573638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774510373629
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