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Mechanical injury polarizes skin dendritic cells to elicit a Th2 response by inducing cutaneous TSLP expression

Atopic dermatitis (AD) is characterized by intense scratching and a Th2 dominated systemic and local immune response to cutaneously introduced antigens. Because scratching inflicts mechanical injury to the skin, we examined the effect of mechanical injury inflicted by tape stripping on the capacity...

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Detalhes bibliográficos
Main Authors: Oyoshi, Michiko K., Larson, Ryan P., Ziegler, Steven F., Geha, Raif S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085022/
https://ncbi.nlm.nih.gov/pubmed/21050944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2010.08.041
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