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Divide and conquer: Blocking graft versus host but not graft versus leukemia T cells with agonist BTLA co-inhibitory signals

One of the main objectives in allogeneic hematopoietic stem cell transplantation (aHSCT) research is the prevention of graft versus host disease (GVHD) while maintaining the graft versus leukemia/lymphoma (GVL) effect. Whether these two responses generated by donor T cells can be sufficiently separa...

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Hlavní autoři: Thangavelu, Govindarajan, Anderson, Colin C
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084956/
https://ncbi.nlm.nih.gov/pubmed/21547036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chim.2.1.15083
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