Parity and HLA alleles in risk of rheumatoid arthritis

Specific HLA II alleles are associated with rheumatoid arthritis (RA) risk and others with protection. Risk-associated alleles encode similar amino acid sequences from 70 through 74 of HLA-DRβ1 (QKRAA, QRRAA, RRRAA), referred to as the “shared epitope” (SE) and protective alleles encode DERAA at the...

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Detalhes bibliográficos
Main Authors: Guthrie, Katherine A, Gammill, Hilary S, Madeleine, Margaret M, Dugowson, Carin E, Nelson, J Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084950/
https://ncbi.nlm.nih.gov/pubmed/21547030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chim.2.1.15424
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