A Genetic Risk Score Combining Ten Psoriasis Risk Loci Improves Disease Prediction

Psoriasis is a chronic, immune-mediated skin disease affecting 2–3% of Caucasians. Recent genetic association studies have identified multiple psoriasis risk loci; however, most of these loci contribute only modestly to disease risk. In this study, we investigated whether a genetic risk score (GRS)...

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Main Authors: Chen, Haoyan, Poon, Annie, Yeung, Celestine, Helms, Cynthia, Pons, Jennifer, Bowcock, Anne M., Kwok, Pui-Yan, Liao, Wilson
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084857/
https://ncbi.nlm.nih.gov/pubmed/21559375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019454
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