Spinal Botulinum Neurotoxin B: Effects on Afferent Transmitter Release and Nociceptive Processing

Botulinum neurotoxin B (BoNT-B) mediates proteolytic cleavage of VAMP I/II (synaptobrevins I/II), which prevents vesicle-membrane fusion and blocks neurotransmitter release. In the present study, we investigated the effects of BoNT-B on neurotransmitter release in vivo from spinal primary afferent s...

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Bibliografiske detaljer
Main Authors: Huang, Polly P., Khan, Imran, Suhail, Mohammed S. A., Malkmus, Shelle, Yaksh, Tony L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084763/
https://ncbi.nlm.nih.gov/pubmed/21559464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019126
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