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WSX1 Expression in Tumors Induces Immune Tolerance via Suppression of Effector Immune Cells

Crosstalk between tumor cells and the cognate microenvironment plays a crucial role in tumor initiation and progression. However, only a few genes are known to affect such a crosstalk. This study reveals that WSX1 plays such a role when highly expressed in tumor cells. The expression of WSX1 in Lewi...

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Detalhes bibliográficos
Main Authors: Dibra, Denada, Cutrera, Jeffry, Xia, Xueqing, Li, Shulin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084744/
https://ncbi.nlm.nih.gov/pubmed/21559505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019072
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