Activation of the innate immune receptor Dectin-1 upon formation of a “phagocytic synapse”

Innate immune cells must be able to distinguish between direct binding to microbes and detection of components shed from the surface of microbes located at a distance. Dectin-1 is a pattern recognition receptor expressed by myeloid phagocytes (macrophages, dendritic cells and neutrophils) that detec...

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Bibliographic Details
Main Authors: Goodridge, Helen S., Reyes, Christopher N., Becker, Courtney A., Katsumoto, Tamiko R., Ma, Jun, Wolf, Andrea J., Bose, Nandita, Chan, Anissa S. H., Magee, Andrew S., Danielson, Michael E., Weiss, Arthur, Vasilakos, John P., Underhill, David M.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084546/
https://ncbi.nlm.nih.gov/pubmed/21525931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10071
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