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Lack of association between the Trp719Arg polymorphism in kinesin-like protein 6 and coronary artery disease in 19 case-control studies

OBJECTIVES: We sought to replicate the association between the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism (rs20455) and clinical coronary artery disease (CAD). BACKGROUND: Recent prospective studies suggest that carriers of the 719Arg allele in KIF6 are at increased risk of clinical CAD co...

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Main Authors: Assimes, Themistocles L, Hólm, Hilma, Kathiresan, Sekar, Reilly, Muredach P, Thorleifsson, Gudmar, Voight, Benjamin F, Erdmann, Jeanette, Willenborg, Christina, Vaidya, Dhananjay, Xie, Changchun, Patterson, Chris C, Morgan, Thomas M, Burnett, Mary Susan, Li, Mingyao, Hlatky, Mark A, Knowles, Joshua W, Thompson, John R, Absher, Devin, Iribarren, Carlos, Go, Alan, Fortmann, Stephen P, Sidney, Stephen, Risch, Neil, Tang, Hua, Myers, Richard M, Berger, Klaus, Stoll, Monika, Shah, Svati H., Thorgeirsson, Gudmundur, Andersen, Karl, Havulinna, Aki S, Herrera, J. Enrique, Faraday, Nauder, Kim, Yoonhee, Kral, Brian G., Mathias, Rasika, Ruczinski, Ingo, Suktitipat, Bhoom, Wilson, Alexander F, Yanek, Lisa R., Becker, Lewis C, Linsel-Nitschke, Patrick, Lieb, Wolfgang, König, Inke R, Hengstenberg, Christian, Fischer, Marcus, Stark, Klaus, Reinhard, Wibke, Winogradow, Janina, Grassl, Martina, Grosshennig, Anika, Preuss, Michael, Eifert, Sandra, Schreiber, Stefan, Wichmann, H-Erich, Meisinger, Christa, Yee, Jean, Friedlander, Yechiel, Do, Ron, Meigs, James B, Williams, Gordon, Nathan, David M, MacRae, Calum A, Qu, Liming, Wilensky, Robert L, Matthai, William H., Qasim, Atif N, Hakonarson, Hakon, Pichard, Augusto D, Kent, Kenneth M, Satler, Lowell, Lindsay, Joseph M, Waksman, Ron, Knouff, Christopher W, Waterworth, Dawn M, Walker, Max C, Mooser, Vincent, Marrugat, Jaume, Lucas, Gavin, Subirana, Isaac, Sala, Joan, Ramos, Rafael, Martinelli, Nicola, Olivieri, Oliviero, Trabetti, Elisabetta, Malerba, Giovanni, Pignatti, Pier Franco, Guiducci, Candace, Mirel, Daniel, Parkin, Melissa, Hirschhorn, Joel N, Asselta, Rosanna, Duga, Stefano, Musunuru, Kiran, Daly, Mark J, Purcell, Shaun, Braund, Peter S, Wright, Benjamin J, Balmforth, Anthony J, Ball, Stephen G, Ouwehand, Willem H, Deloukas, Panos, Scholz, Michael, Cambien, Francois, Huge, Andreas, Scheffold, Thomas, Salomaa, Veikko, Girelli, Domenico, Granger, Christopher B., Peltonen, Leena, McKeown, Pascal P, Altshuler, David, Melander, Olle, Devaney, Joseph M, Epstein, Stephen E, Rader, Daniel J, Elosua, Roberto, Engert, James C, Anand, Sonia S, Hall, Alistair S, Ziegler, Andreas, O’Donnell, Christopher J, Spertus, John A, Siscovick, David, Schwartz, Stephen M, Becker, Diane, Thorsteinsdottir, Unnur, Stefansson, Kari, Schunkert, Heribert, Samani, Nilesh J, Quertermous, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084526/
https://ncbi.nlm.nih.gov/pubmed/20933357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2010.06.022
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