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FLIM FRET Technology for Drug Discovery: Automated Multiwell-Plate High-Content Analysis, Multiplexed Readouts and Application in Situ**
A fluorescence lifetime imaging (FLIM) technology platform intended to read out changes in Förster resonance energy transfer (FRET) efficiency is presented for the study of protein interactions across the drug-discovery pipeline. FLIM provides a robust, inherently ratiometric imaging modality for dr...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
WILEY-VCH Verlag
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084521/ https://ncbi.nlm.nih.gov/pubmed/21337485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphc.201000874 |
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