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High levels of synaptosomal Na(+)-Ca(2+) exchangers (NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affected by Alzheimer’s disease

Synaptosomal expression of NCX1, NCX2, and NCX3, the three variants of the Na(+)-Ca(2+) exchanger (NCX), was investigated in Alzheimer’s disease parietal cortex. Flow cytometry and immunoblotting techniques were used to analyze synaptosomes prepared from cryopreserved brain of cognitively normal age...

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Detalhes bibliográficos
Main Authors: Sokolow, Sophie, Luu, Sanh H., Headley, Alison J., Hanson, Alecia Y., Kim, Taeree, Miller, Carol A., Vinters, Harry V., Gylys, Karen H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084347/
https://ncbi.nlm.nih.gov/pubmed/21382638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2010.12.008
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