Inactivation of the DNA Repair Genes mutS, mutL or the Anti-Recombination Gene mutS2 Leads to Activation of Vitamin B(1) Biosynthesis Genes

Oxidative stress generates harmful reactive oxygen species (ROS) that attack biomolecules including DNA. In living cells, there are several mechanisms for detoxifying ROS and repairing oxidatively-damaged DNA. In this study, transcriptomic analyses clarified that disruption of DNA repair genes mutS...

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Main Authors: Fukui, Kenji, Wakamatsu, Taisuke, Agari, Yoshihiro, Masui, Ryoji, Kuramitsu, Seiki
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084264/
https://ncbi.nlm.nih.gov/pubmed/21552516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019053
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