Dendritic Cells Crosspresent Antigens from Live B16 Cells More Efficiently than from Apoptotic Cells and Protect from Melanoma in a Therapeutic Model

Dendritic cells (DC) are able to elicit anti-tumoral CD8(+) T cell responses by cross-presenting exogenous antigens in association with major histocompatibility complex (MHC) class I molecules. Therefore they are crucial actors in cell-based cancer immunotherapy. Although apoptotic cells are usually...

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Autores principales: Matheoud, Diana, Baey, Camille, Vimeux, Lene, Tempez, Andy, Valente, Michael, Louche, Pauline, Le Bon, Agnès, Hosmalin, Anne, Feuillet, Vincent
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084260/
https://ncbi.nlm.nih.gov/pubmed/21552572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019104
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