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Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor

PURPOSE: The sigma-1 receptor (σR1), a ligand-operated chaperone, has been inferred to be neuroprotective in previous studies using σR1 ligands. The σR1 specificity of the protective function, however, has yet to be firmly established, due to the existence of non-σR1 targets of the ligands. Here, we...

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Detalhes bibliográficos
Main Authors: Mavlyutov, Timur A., Nickells, Robert W., Guo, Lian-Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084245/
https://ncbi.nlm.nih.gov/pubmed/21541278
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